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35+ Years Treating Hemophilia

CSL Behring has over 35 years of experience in the field of hematology. From disorders that span the coagulation cascade to the management of urgent reversal of acquired bleeding, CSL Behring continues to invest in this area and remains committed to continuing our innovations in this field.

Factor XIII Deficiency

Congenital factor XIII deficiency is an autosomal recessive disorder.

Acquired factor XIII deficiency can be seen in the setting of cardiac surgery, malignancy, infection and irritable bowel disease.

Caused by mutations in the genes that code for either FVIII subunit A or B (rarer).

Most common bleeding sites include umbilical stump, soft tissue, surgical and intracranial.

Poor wound healing is often present.

Measure FXIII activity.

PT, aPTT, and thrombin time are usually normal.
Genetic analysis to identify gene mutation.

Prophylaxis recommended especially with levels <10%

For U.S. Healthcare Professionals only
For U.S. Healthcare Professionals only

The purpose of this CSL Behring Medical Affairs website is to support Healthcare Professionals with scientific information. This website is also a channel for U.S. Healthcare Professionals to submit questions or connect with CSL Behring U.S. Healthcare Professionals. The information provided is for educational purposes only and is not intended to promote any products. By continuing to use this site you are acknowledging that you are a US Healthcare Professional

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